Biological and Analytical Investigations of Alpha-Glucosidase Inhibitory and Anti-Oxidant Activities on Selected Malaysian Medicinal Plants

This study was performed to establish anti-diabetic and anti-oxidant properties, carry out phytochemical analysis of selected local plants which are traditionally used as medicinal plants. Local involved in this were Lawsonia inermis, Punica granatum, Dryobalanops aromatica, Ziziphus mauritiana, Ocimum basilicum. Solvent extraction using maceration method with solvents increasing polarity. Alpha-glucosidase inhibition assay on all extracts ascertain their potentials. The screened for antioxidant activity assays (FRAP, DPPH, TAOC, ABTS, BCB) quantitative analyses (TPC TFC). Chemical profiling LCMS GCMS high biological activities. Methanol D. aromatica bark leaves showed the most potent alpha-glucosidase IC50 values 0.63 ± 0.03 µg/mL 0.98 0.02 µg/mL, respectively. Both exhibited similar five possessed phenolic contents 266.79 261.69 GAE, results obtained suggested that amongst studied, (via alpha-glucosidase). is first report highlights potential aromatica.